2'-deoxyuridines with a 5-heteroaromatic substituent: synthesis and biological evaluationLUYTEN, I; JIE, L; DE CLERCQ, E et al.Antiviral chemistry & chemotherapy. 1995, Vol 6, Num 4, pp 262-270, issn 0956-3202Article

The relationship between magnetic resonance diffusion imaging and autoradiographic markers of cerebral blood flow and hypoxia in an animal stroke modelLYTHGOE, M. F; WILLIAMS, S. R; BUSZA, A. L et al.Magnetic resonance in medicine. 1999, Vol 41, Num 4, pp 706-714, issn 0740-3194Article

The synthesis of novel 5-trifluoroethoxy pyrimidine nucleosidesKUMAR, P; WIEBE, L. I.Nucleosides & nucleotides. 1990, Vol 9, Num 6, pp 861-873, issn 0732-8311, 13 p.Article

Synthesis of novel fluorinated 2'-3'-dideoxynucleosidesKUMAR, P; WIEBE, L. I.Nucleosides & nucleotides. 1992, Vol 11, Num 2-4, pp 401-416, issn 0732-8311Article

The synthesis of novel 5-trifluoroethyl ethers of thymidineKUMAR, P; WIEBE, L. I.Nucleosides & nucleotides. 1990, Vol 9, Num 6, pp 847-859, issn 0732-8311, 13 p.Article

Synthesis, in vitro anti-human immunodeficiency virus structure-activity relationships and biological stability of 5'-O-myristoyl analogue derivatives of 3'-azido-2', 3'-dideoxythymidine (AZT) as potential prodrugsPARANG, K; WIEBE, L. I; KNAUS, E. E et al.Antiviral chemistry & chemotherapy. 1998, Vol 9, Num 4, pp 311-323, issn 0956-3202Article

Pharmacokinetics and tissue distribution of (± )-3'-azido-2', 3'-dideoxy-5'-o-(2-bromomyristoyl)thymidine, a prodrug of 3'-azido-2', 3'-dideoxythymidine (AZT) in micePARANG, K; WIEBE, L. I; KNAUS, E. E et al.Journal of pharmacy and pharmacology. 1998, Vol 50, Num 9, pp 989-996, issn 0022-3573Article

Synthesis and antiviral activity of novel 5-(1-azido-2-haloethyl) and 5-(1-azido-, amino-, or methoxyethyl) analogs of 2'-deoxyuridineRAKESH KUMAR; WIEBE, L. I; KNAUS, E. E et al.Journal of medicinal chemistry (Print). 1993, Vol 36, Num 17, pp 2470-2474, issn 0022-2623Article

The determination of platinum in biological tissue by instrumental neutron activation analysisHAVERLAND, G. W; WIEBE, L. I.International journal of radiation applications and instrumentation. Part A. Applied radiation and isotopes. 1991, Vol 42, Num 8, pp 775-776, issn 0883-2889, 2 p.Article

Synthesis and antiviral activity of 5-ethyl-5-halo-6-alkoxy-(or azido)-5,6-dihydro-2'-deoxyuridine diastereomers as potential prodrugs to 5-ethyl-2'-deoxyuridineKUMAR, R; WIEBE, L. I; KNAUS, E. E et al.Archiv der Pharmazie (Weinheim). 1997, Vol 330, Num 8, pp 259-263, issn 0365-6233Article

Synthesis and antiviral activity of 1-β-D-arabinofuranosyluracils and uridines containing 5-[2-bromo-2-chloro (or bromo)-1-hydroxy (or methoxy) ethyl] substituentsRAKESH KUMAR; WIEBE, L. I; KNAUS, E. E et al.Nucleosides & nucleotides. 1993, Vol 12, Num 5, pp 537-545, issn 0732-8311Article

Syntheses and biological evaluation of 5'-O-myristoyl derivatives of thymidine against human immunodeficiency virusPARANG, K; WIEBE, L. I; KNAUS, E. E et al.Antiviral chemistry & chemotherapy. 1997, Vol 8, Num 5, pp 417-427, issn 0956-3202Article

α-trifluoremethyl-β-ureido-propionic acid (F₃MUPA) : a new metabolite of trifluridine (F₃TdR)TANDON, M; KUMAR, P; WIEBE, L. I et al.Nucleosides & nucleotides. 1993, Vol 12, Num 8, pp 803-814, issn 0732-8311Article

Drug-induced perturbations in the in vivo distribution of oncological radiotracers. I: 5-Fluoro-6-³H-2'-deoxyuridine influenced by nitrobenzylthioinosine 5'-phosphate (NBMPR-P)WIEBE, L. I; KNAUS, E. E.Nuclear medicine and biology. 1986, Vol 13, Num 3, pp 257-259, issn 0969-8051Article

Synthesis of (E)-5-(2-iodovinyl)-3'-O-(1-methyl-1,4-dihydropyridyl-3-carbonyl)-2'-fluoro-2'-deoxyuridine (IVFRU-CDS) for brain targeted delivery of IVFRU, and antiviral nucleosideRAKESH KUMAR; KNAUS, E. E; WIEBE, L. I et al.Nucleosides & nucleotides. 1993, Vol 12, Num 9, pp 895-904, issn 0732-8311Article

Synthesis and anti-HIV activity of 3'-O-formyl derivatives of thymidine and 2'-deoxyuridineRAKESH KUMAR; KNAUS, E. E; WIEBE, L. I et al.Nucleosides & nucleotides. 1992, Vol 11, Num 6, pp 1219-1228, issn 0732-8311Article

Concepts for the design of anti-HIV nucleoside prodrugs for treating cephalic HIV infectionWIEBE, L. I; KNAUS, E. E.Advanced drug delivery reviews. 1999, Vol 39, Num 1-3, pp 63-80, issn 0169-409XArticle

Nitroimidazole adducts as markers for tissue hypoxia : mechanistic studies in aerobic normal tissues and tumour cellsPARLIAMENT, M. B; WIEBE, L. I; FRANKO, A. J et al.British journal of cancer. 1992, Vol 66, Num 6, pp 1103-1108, issn 0007-0920Article

Animal tumor models for the evaluation of In-vivo diagnostic radiotracersWIEBE, L. I; ALLALUNIS-TURNER, J; FRANKO, A et al.American journal of physiologic imaging. 1991, Vol 6, Num 3, pp 133-149, issn 0885-8276Article

Synthesis of ¹³¹I, ¹²⁵I and ⁸²Br labelled (E)-5-(2-halovinyl)-2'-deoxyuridinesSAMUEL, J; KNAUS, E. E; WIEBE, L. I et al.The International journal of applied radiation and isotopes. 1984, Vol 35, Num 11, pp 1049-1052, issn 0020-708XArticle

Non-invasive scintigraphic monitoring of gene expression in a HSV-1 thymidine kinase gene therapy modelMORIN, K. W; KNAUS, E. E; WIEBE, L. I et al.Nuclear medicine communications. 1997, Vol 18, Num 7, pp 599-605, issn 0143-3636Article

Bioavailability and pharmacokinetic parameters for 5-ethyl-2'-deoxyuridineMAJID CHERAGHALI, A; KNAUS, E. E; WIEBE, L. I et al.Antiviral research. 1994, Vol 25, Num 3-4, pp 259-267, issn 0166-3542Article

Synthesis, in vitro biological stability, and anti-HIV activity of 5-halo-6-alkoxy(or azido)-5,6-dihydro-3'-azido-3'-deoxythymidine diastereomers as potential prodrugs to 3'-azido-3'-deoxythymidine (AZT)RAKESH KUMAR; WANG, LM; WIEBE, L. I et al.Journal of medicinal chemistry (Print). 1994, Vol 37, Num 25, pp 4297-4306, issn 0022-2623Article

Synthesis of brain-targeted 1-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-(E)-5-(2-iodovinyl)uracil coupled to a dihydropyridine ↔pyridinium salt redox chemical-delivery systemMORIN, K. W; WIEBE, L. I; KNAUS, E. E et al.Carbohydrate research. 1993, Vol 249, Num 1, pp 109-116, issn 0008-6215Article

Detection of new metabolites of trifluridine (F₃TdR) using ¹⁹F NMR spectroscopyTANDON, M; KUMAR, P; WIEBE, G et al.Biochemical pharmacology. 1992, Vol 44, Num 11, pp 2223-2228, issn 0006-2952Article